Principal Research Scientist I (all genders) Medicinal Chemistry (permanent / full-time) (m/w/d)

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AbbVie Deutschland GmbH & Co. KG
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Veröffentlicht: 16.12.2024 Arbeitsort: 67061 Koeln
AbbVie's mission is to discover and deliver innovative medicines and
solutions that solve serious health issues today and address the medical
challenges of tomorrow. We strive to have a remarkable impact on people's
lives across several key therapeutic areas – immunology, oncology,
neuroscience, and eye care – and products and services in our Allergan
Aesthetics portfolio. For more information about AbbVie, please visit us at
www.abbvie.com

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Moving mountains together – as

Principal Research Scientist I (all genders) Medicinal Chemistry (permanent /
full-time)

The job that makes possibilities real in patients' lives. And yours.

The job that helps you get ahead in life. Moving mountains together.

Welcome to AbbVie! As part of an international company with 48,000 employees
worldwide and around 3,000 employees in Germany, you will have the opportunity
of addressing some of tomorrows unmet medical needs in close collaboration with
your colleagues. Are you passionate about improving global health care? Do you
want to contribute to improving patients' quality of life through your
expertise? In a challenging work environment that offers opportunities of
developing and increasing your own skills? You've come to the right place!

Small Molecular Therapeutics and Platform Technologies (SMTPT) within
Discovery Research in Ludwigshafen (Germany) seeks an accomplished scientist to
lead a team of medicinal chemists within the Global Medicinal Chemistry (GMEC)
organization. GMEC is committed to delivering first and best-in-class small
molecules in conventional and unconventional drug-like space with the potential
to improve human health. The Principal Research Scientist will lead a team of
chemists designing and synthesizing small molecules aimed at identifying and
advancing promising low dose leads.

They will be responsible for managing a diverse team of scientists who design
and synthesize drug candidates for novel targets throughout AbbVie’s
drug discovery pipeline, and may serve as Medicinal Chemistry Lead for some of
these efforts. She / He / They will have a strong background in synthetic
chemistry who has demonstrated high productivity in synthesizing complex
organic molecules. She / He / They and team will develop novel medicinal
chemistry strategies and execute multiparametric optimization(s) of drug
candidate properties in a highly collaborative environment aimed at
accelerating the delivery of a sustainable pipeline of first in class /
breakthrough small molecule drug candidates with transformative potential.

The candidate will have experience with strategic planning, and leadership of
medicinal chemistry teams, as well as working with cross-functional teams. The
candidate will have a strong expertise in modern medicinal chemistry, including
an appreciation of modern computational and experimental tools,
multidisciplinary inputs, and synthetic technologies needed to develop low dose
small molecule drug candidates. The ideal candidate will be able to lead by
influence in a matrix environment and maintain a productive, collaborative, and
inclusive environment. Strong communication skills are essential, as the
candidate must be able to tailor interactions with technical teams and
represent the medicinal chemistry advances to AbbVie leadership.

Responsibilities

* In your role, you will lead international Medicinal Chemistry teams and
partner cross-functionally to advance projects by applying state-of-the-art
methodologies in drug discovery
* You will lead internal Medicinal Chemistry teams and/or steer teams at our
CRO partners in the design and synthesis of low dose drug candidates and the
development of stage-appropriate progression funnels for their identification
from research to development
* As programs advance, work with key stakeholders in the Development sciences
core team to address and reduce risks in collaboration to drive towards
candidate nomination
* Lead chemistry team activities and maintain a high level of productivity in
the laboratory setting
* Promote professional development of a team of scientists through effective
mentoring, guidance, and supervision
* Identify and integrate emerging scientific trends from internal and
external sources into functional objectives
* Present program updates and research strategies to functional and
non-functional leaders as well as potential and existing partners
* Maintain awareness of emerging literature and science in the field and
author scientific disclosures / publications
* Maintain scientific presence outside AbbVie with appropriate publication
and conference abstract submission highlighting innovative medicinal chemistry
learnings
* A mix of on-site and remote working will be possible in alignment with the
role responsibilities
Qualifications

* PhD with typically 6+ years of experience in organic or medicinal chemistry
or equivalent field with 6+ years of relevant work experience in biotech or
pharma. BS or equivalent education and extensive, Typically, 14+ years of
experience; MS or equivalent education with typically 12+ years of experience
* Extensive knowledge and experience in modern medicinal chemistry,
preferably also in the field of protein degradation and CNS-drug development
* Highly organized and self-directed, experience leading medicinal chemistry
teams
* Proven track record of productivity in the laboratory setting
* Excellent written and verbal communication is required, as well as critical
evaluation and data-driven decision-making
* Highly collaborative, team-oriented, and considerate of the needs of others
* Strong interpersonal skills and ability to collaborate with diverse groups
within the organization and external partners
* Proven chemistry team leadership and management abilities, including
experience mentoring, guiding, supervising, and developing early career chemists
* Ability to create an inclusive environment where diverse ideas, viewpoints
and backgrounds are valued; willingness and ability to lead inclusively and
demonstrate a commitment to listen and consider all points of view
Here's how we can move mountains together

* with a diverse work environment where you can have a real impact
* with an open corporate culture
* with an attractive salary
* with an intensive onboarding process with a mentor at your side
* with flexible work models for a healthy work-life balance
* with a corporate health management that offers comprehensive health and
exercise programs
* with company social benefits
* with a wide range of career opportunities in an international organization
* with top-tier, attractive development opportunities
* with a strong international network
Multiple times, we have been globally recognized as a "Great Place to
Work" and we are proud to provide our employees with the flexibility to
maintain a healthy work-life balance. We take our impact on the environment and
our communities seriously and therefore focus on giving something back on a
regular basis. We are committed to equality, equity, diversity and inclusion
(EED&I) – a commitment that is fundamental to us. This includes
appreciating different perspectives, creating an inclusive culture and treating
all employees with dignity and respect.

At AbbVie, your individual contributions count – help us move mountains
together. Be a part of our success, grow with us and accomplish more than you
could have imagined. Sounds like the perfect career opportunity for you? We
look forward to receiving your application! All you need is a complete CV
– we will discuss everything else with you in person.

Join our team

Any questions? Feel free to email as at TalentAcquisition.de@abbvie.com

– we look forward to hearing from you!

PEOPLE. PASSION. POSSIBILITIES.
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